Study finds possible early predictor of successful transcranial magnetic stimulation therapy for major depression
- Cadiz Salazar
- Jan 29
- 1 min read
Updated: Jan 31
UCLA Health researchers have made exciting discoveries about repetitive Transcranial Magnetic Stimulation (rTMS) for treating depression.
Effectiveness of rTMS
- 54% of patients showed significant improvement in mood symptoms (at least 50% reduction).
- rTMS was effective even for patients who had not responded to multiple antidepressant medications.
Rapid Results
- Patients often reported improvement within the first week of treatment.
- This is faster than previously thought, though full benefits still develop over several weeks.
Treatment Approach
- UCLA uses a "precision TMS" model:
- Patients see a psychiatrist at every treatment session.
- Symptoms are measured weekly using multiple rating scales.
- Treatment typically involves 20-30 minute sessions, five days a week, for 6-8 weeks.
Improved Assessment
- Using multiple depression rating scales provides a more accurate picture of treatment effectiveness.
- Up to one-third of positive responses could be missed if only one scale is used.
Early Prediction of Success
- Improvements seen within the first 5-10 treatments can predict overall treatment success.
- This insight could help doctors adjust treatment plans more effectively.
About rTMS
- Approved by the FDA in 2008 for treatment-resistant major depressive disorder.
- Uses magnetic fields to stimulate specific brain circuits involved in mood regulation.
This research offers hope for more effective and personalized depression treatment, especially for those who haven't responded well to traditional medications.
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